Episode 306

Psychedelics & Mortality

A Conversation with Roland Griffiths

December 13, 2022

Sam Harris speaks with Roland Griffiths about psychedelics and mortality. They discuss the current state of psychedelic research, the timeline for FDA approvals, the risks to mental health posed by psychedelics in vulnerable populations, the use of psychedelics among the well, the relationship between psychedelics and meditation, advice for “bad” trips, microdosing, Roland’s stage-4 cancer diagnosis, reflections on death, and other topics.

Roland Griffiths, Ph.D., is a Professor in the Departments of Psychiatry and Neurosciences at the Johns Hopkins University School of Medicine, and founding Director of the Johns Hopkins Center on Psychedelic and Consciousness Research. He is author of 420 journal articles and book chapters, and has trained more than 50 postdoctoral research fellows. Roland has been a consultant to the National Institutes of Health, to numerous pharmaceutical companies in the development of new psychotropic drugs, and as a member of the Expert Advisory Panel on Drug Dependence for the World Health Organization. Roland has a long-term meditation practice and has been conducting human research with psychedelics for more than 20 years.

Website: Griffithsfund.org, Endowment Funding Letter, hopkinspsychedelic.org


Learning how to train your mind is the single greatest investment you can make in life. That’s why Sam Harris created the Waking Up app. From rational mindfulness practice to lessons on some of life’s most important topics, join Sam as he demystifies the practice of meditation and explores the theory behind it.